research sourcing
Commissioning a sequencing or proteomics study
Commission sequencing or proteomics by locking the question, the reference database, sample QC and the deliverable before a library or a digest is made.
8 October 2026 · 10 min read
Tag
study design
Articles tagged study design. Tags group methods across clusters so a technique can be found from more than one route.
All topicsBuffers and laboratory water26Cell culture26Chromatography26Cold chain and sample storage26Cytometry and microscopy26DNA sequencing26Gels and blotting26Gene expression26Genome editing26Immunoassays26Laboratory labware26Laboratory safety26Liquid handling26Microbiology26Molecular cloning26Nucleic acid purification26PCR and amplification26Protein biochemistry26Proteomics26Research sourcing and study design26
cold chainbiosafetycrisprspecificationsequencingproteomicsenquiryglossarytroubleshootingcloningmicrobiologybuffersfreezerspipettingcalibrationelisacell cultureglassware
8 articles
gene expression
How many replicates a simple design needs to discuss
What to write when a simple expression design asks for replicates: the biological unit, why one sample cannot carry a treatment claim, and why pilots exist.
8 October 2026 · 9 min read
research sourcing
Multi-item quotes and one scientific aim
Group quotation lines under one experiment and mark the reagent the aim cannot survive without, so a long cart cannot hide a gap.
8 October 2026 · 9 min read
research sourcing
Pilot samples before a large cohort
Separate what a pilot may decide, such as yield, library QC, and logistics, from the biological effect only a designed cohort can support.
8 October 2026 · 9 min read
proteomics
Questions before a proteomics enquiry
Questions to write down before a proteomics enquiry: contrast, matrix, replicates, detergents, modifications, database, shipping temperature and the report
8 October 2026 · 8 min read
dna sequencing
Questions for a Sanger versus NGS decision
Questions that separate a Sanger trace from a short-read pool: one amplicon, a mixture, a haplotype, a plasmid junction. Turnaround is asked, not promised.
8 October 2026 · 8 min read
proteomics
Sample randomisation and batch design
How sample randomisation and blocking stop a processing day from masquerading as biology, and why a confounded proteomics batch often cannot be rescued later.
8 October 2026 · 7 min read
dna sequencing
What to put in a sequencing statement of work
The lines a sequencing statement of work needs: organism, geometry, depth, reference build, files, retention and the rule for a failed sample.
8 October 2026 · 7 min read