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difficult samples

Articles tagged difficult samples. Tags group methods across clusters so a technique can be found from more than one route.

All topicsBuffers and laboratory water26Cell culture26Chromatography26Cold chain and sample storage26Cytometry and microscopy26DNA sequencing26Gels and blotting26Gene expression26Genome editing26Immunoassays26Laboratory labware26Laboratory safety26Liquid handling26Microbiology26Molecular cloning26Nucleic acid purification26PCR and amplification26Protein biochemistry26Proteomics26Research sourcing and study design26
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1 article

Gloved hand closing the lid of a benchtop PCR thermal cycler holding a strip of PCR tubes, city lights at dusk behind

nucleic acid purification

Removing PCR inhibitors from difficult samples

Pick dilution, a further cleanup, or an inhibitor-tolerant polymerase when heme, humic acid, heparin or leftover solvent stops a PCR.

8 October 2026 · 9 min read