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proteomics

Articles tagged proteomics. Tags group methods across clusters so a technique can be found from more than one route.

16 articles

Mass spectrometer coupled to a liquid chromatography system with sample vials in the foreground

proteomics

Sample randomisation and batch design

How sample randomisation and blocking stop a processing day from masquerading as biology, and why a confounded proteomics batch often cannot be rescued later.

8 October 2026 · 7 min read

Mass spectrometer coupled to a liquid chromatography system with sample vials in the foreground

proteomics

Targeted MRM versus discovery runs

When to screen with a discovery run and when to confirm with targeted MRM: peptide choice, transitions, a matrix blank and a calibration or labelled standard.

8 October 2026 · 8 min read

Mass spectrometer coupled to a liquid chromatography system with sample vials in the foreground

proteomics

Troubleshooting sparse identifications

Sparse proteomics identifications: check peptide amount, chromatogram shape, detergent humps, the search database, cysteine chemistry and whether only keratin

8 October 2026 · 8 min read

Mass spectrometer coupled to a liquid chromatography system with sample vials in the foreground

proteomics

What a proteomics report should state

A proteomics report a second lab can audit names groups, digestion, the database version, FDR cut-offs, normalisation and the missing-value rule.

8 October 2026 · 8 min read