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spike in

Articles tagged spike in. Tags group methods across clusters so a technique can be found from more than one route.

2 articles

Gloved hand closing the lid of a benchtop PCR thermal cycler holding a strip of PCR tubes, city lights at dusk behind

pcr amplification

Inhibition of PCR by sample contaminants

Separate a true PCR negative from a dead tube when heme, humic acids, ethanol, guanidine, heparin, bile salts or excess DNA may be present.

8 October 2026 · 8 min read

Gloved hand closing the lid of a benchtop PCR thermal cycler holding a strip of PCR tubes, city lights at dusk behind

nucleic acid purification

Removing PCR inhibitors from difficult samples

Pick dilution, a further cleanup, or an inhibitor-tolerant polymerase when heme, humic acid, heparin or leftover solvent stops a PCR.

8 October 2026 · 9 min read