cold chain
Power cuts and a freezer alarm
A freezer alarm only helps if a written response names who is called, how long the door stays shut, and where the backup sits.
8 October 2026 · 9 min read
Knowledge centre
Methods a laboratory can check.
Guides, method explainers and sourcing notes for research laboratories. Written by the EVRINTH Editorial Team from published methods, with catalogue links for enquiry rather than stock claims.
All topicsBuffers and laboratory water26Cell culture26Chromatography26Cold chain and sample storage26Cytometry and microscopy26DNA sequencing26Gels and blotting26Gene expression26Genome editing26Immunoassays26Laboratory labware26Laboratory safety26Liquid handling26Microbiology26Molecular cloning26Nucleic acid purification26PCR and amplification26Protein biochemistry26Proteomics26Research sourcing and study design26
cold chainbiosafetycrisprspecificationsequencingproteomicsenquiryglossarytroubleshootingcloningmicrobiologybuffersfreezerspipettingcalibrationelisacell cultureglassware
520 articles
gels and blotting
Power supplies voltage and run time
Choose agarose voltage from electrode distance and the sharpness you need, and allow for heat, spent buffer, and a power cut.
8 October 2026 · 8 min read
laboratory safety
PPE that matches the task
Match the coat, the gloves, and the eye protection to the route a splash or a contamination would take. Extra layers are not automatically safer.
8 October 2026 · 9 min read
liquid handling
Pre-wetting tips and volatile solvents
See why pre-wetting saturates the air cushion, why ethanol-class solvents still drip, and when positive displacement is the better class.
8 October 2026 · 7 min read
laboratory safety
Pregnancy and specific agents need occupational advice
Some agents are a question for occupational health, not for a seller. This guide separates a catalogue line from an assessment a clinician must own.
8 October 2026 · 9 min read
buffers and water
Preparing a buffer and checking pH
Prepare a buffer at a stated pH and temperature, record the salt form, and treat a drifting electrode or a bad slope as a failed control.
8 October 2026 · 11 min read
proteomics
Preparing peptides for mass spectrometry
How laboratories prepare peptides for mass spectrometry: reduction, alkylation, digestion, cleanup, and the clues that a digest failed.
8 October 2026 · 7 min read
cell culture
Primary cells versus continuous lines
How finite primary cultures differ from continuous lines in lifespan, donor variation and contamination risk, and why a paper's doses do not transfer.
8 October 2026 · 7 min read
genome editing
Prime editing in plain language
Prime editing writes a short new sequence from a pegRNA, using a nick and reverse transcriptase, without a double-stranded DNA donor.
8 October 2026 · 10 min read
pcr amplification
Primer design for endpoint PCR
Choose an endpoint PCR primer pair by 3-prime match, dimer risk, and an amplicon a gel can separate from primer-dimer. Primer-BLAST is only a check.
8 October 2026 · 8 min read
molecular cloning
Promoters tags and reading frames
How to check a promoter, a fusion tag and the reading frame on a plasmid map before you transform, including the ribosome binding site, stops and the junction.
8 October 2026 · 10 min read
protein biochemistry
Protease inhibitors and when they interfere
Protease inhibitor classes stop different enzymes. EDTA, PMSF, AEBSF, pepstatin and leupeptin can also block the activity or the resin you wanted.
8 October 2026 · 6 min read